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WaRM2 Lab

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Who we are

The Eduardo Nicolau Laboratory is dedicated to the design, synthesis, and modification of soft materials, with a cenral emphasis on understanding their interactions with biological molecules. Our research program pursues both fundamental questions and urgent societal challenges, working at the interface of chemistry, biology, and environmental sciences.

Our main areas of investigation include:

1. Next-generation water purification membranes to improve efficiency and sustainability.
2. Polymer–peptide conjugates for applications in tissue regeneration and antimicrobial catheter coatings.
3. Aptamer-based biosensors for sensitive and selective detection of biological targets.
4. Energy storage and batteries to enable safer, longer-lasting, and more sustainable technologies.
5. Air purification materials to improve indoor and outdoor air quality.

Through this diverse research portfolio, we aim to contribute to solutions for pressing global issues: access to clean water, clean air, reliable energy storage, and advanced medical equipment. To achieve these goals, we employ a wide array of techniques, including polymer chemistry, molecular biology, microscopy, and electrochemical methods, creating a highly interdisciplinary environment that supports innovation and discovery.

Research news

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EN Lab Team Fall 2025

News

Recent Publications

  1. J Santillán, E Nicolau, et al. Electrosprayed Nanohydroxyapatite and Nanodiamonds as Biocompatible Additives for Cellulose-based Scaffolds: Applications to Bone Tissue Regeneration. To be submitted (2023) 
  2. G. C. Del Valle-Pérez, J. C. Muñoz-Senmache, P. Cruz-Tato, E. Nicolau and A. J. Hernandez-Maldonado. Trace CO2 Removal from Humid Atmosphere by a Hierarchical Silicoaluminophosphate/Carbon Composite Adsorbent. ACS Applied Engineering Materials (2023). DOI: 10.1021/acsaenm.2c00208 
  3. Xaimara Santiago-Maldonado1, José A. Rodríguez-Martínez2, Marvin J. Bayro1,3, Eduardo Nicolau1In Vitro Selection and Characterization of Single-Stranded DNA Molecular Recognition Elements Against Cyanotoxin L-BMAA. In preparation for submission to ACS Biomacromolecules (2023) 
  4. Samir Bello, Osvaldo Rodriguez, Junellie Cruz, and Eduardo Nicolau Bioactive scaffolds as a promising alternative for enhancing critical-size bone defect regeneration in the craniomaxillofacial region. Accepted for publication in ACS Applied Bio Materials (2023) 
  5. Eduardo Nicolau, Liz Santiago-Martoral, Adrialis Figueroa, Perla Cruz-Tato, Alondra Rodríguez-Rolón, and Luis Bermúdez-Morales, Lyotropic liquid crystals – urease biocatalytic membrane: An in-situ FO filtration and urea degradation study under different gravity environments, Under review in Nature Microgravity (2023) 
  6. Cruz-Tato, Perla; Penabad, Laura; Lasalde, Cesar; Rodríguez-Rolón, Alondra; Nicolau, Eduardo. Assessing a Multilayered Hydrophilic - Electrocatalytic Forward Osmosis Membrane for Ammonia Electro-Oxidation Submitted to ACS Environmental Science and Technology (2023) 
  7. Luis Bermúdez-Morales, Leonardo Lizardi, Liz Santiago-Martoral, Perla Cruz-Tato, and Eduardo Nicolau Zwitterionic and Photocatalytic Janus Membrane Based on Diethylamine N-Oxide Group and WS2 Nanosheets for Dye Removal in Forward Osmosis ACS Applied Engineering Materials 2023 1 (8), 2236-2246 
  8. Jessika Pazol, Perla Cruz-Tato, and Eduardo Nicolau Characterization of a Model Bioreactive Membrane for the Simultaneous Separation and Hydrolysis of Lipopolysaccharides ACS Applied Engineering Materials 2023 1 (6), 1684-1697 ​

Funding sources


  • NASA EPSCoR # NNX14AN18A
  • NASA ASTAR # NNX15AU27H
  • NASA Space Grant: NNX15AI11H
  • NASA MIRO/PR-SPRInT: 80NSSC19M0236
  • NSF-PRLSAMP: HRD 1400868
  • NSF Bridge to the Doctorate: HRD 1612393
  • NIH MARC & RISE Program: 5R25GM061151-15
  • ​NIH-SC1: 1SC1GM127220
  • ​NSF-CREST (CIREEN): HRD-1736093
  • NSF-EPSCoR (CAWT):​​ 1849243
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